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WT FSP1 in Cas9 control and FLAD1 KO cells was highly stable with a half-life of approximately 24 h, whereas WT FSP1 in RFK KO cells exhibited significantly reduced stability with a half-life of approximately 6 h (Fig

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It is likely an adaptive stress response induced by a disturbance of homeostasis caused by low levels of biotic or abiotic stimuli (Vargas-Hernandez et al., 2017)